Rabeprazole for Injection (Rabilax 20)
Description
Rabilax 20 Injection contains Rabeprazole 20 mg, a potent proton pump inhibitor (PPI) used for rapid suppression of gastric acid secretion. It is ideal for hospital and emergency settings where oral administration is not feasible.
Composition
- Rabeprazole Sodium equivalent to Rabeprazole – 20 mg
- Lyophilized powder for reconstitution (IV use only)
Mechanism of Action
Rabeprazole works by irreversibly inhibiting the gastric proton pump (H⁺/K⁺-ATPase) in parietal cells, effectively blocking the final step of acid production and providing sustained acid suppression.
Indications
Rabilax 20 is indicated for:
- Gastroesophageal Reflux Disease (GERD)
- Peptic ulcer disease (gastric & duodenal ulcers)
- Erosive esophagitis
- Zollinger–Ellison syndrome
- Stress ulcer prophylaxis in critically ill patients
- Upper gastrointestinal bleeding
Dosage & Administration
- Administered via intravenous injection or infusion
- Typical dose: 20 mg once daily or as directed by physician
- Transition to oral therapy when possible
For IV use only under medical supervision.
Key Benefits
- Fast onset acid suppression
- Effective in acute and critical care scenarios
- Helps in ulcer healing and bleeding control
- Suitable alternative when oral PPIs are not possible
Precautions
- Use cautiously in hepatic impairment
- Long-term use may lead to vitamin B12 deficiency
- Monitor magnesium levels in prolonged therapy
- Exclude gastric malignancy before extended use
Possible Side Effects
- Headache
- Nausea, vomiting
- Diarrhea or constipation
- Injection site reactions
- Rare: hypersensitivity reactions
Storage
- Store below 25°C, protected from light
- Use immediately after reconstitution
Packaging
- Available as 20 mg lyophilized sterile vial
