Piperacillin & Tazobactam for Injection USP – TAZOWELL-4.5

Description

TAZOWELL-4.5 Injection is a potent, broad-spectrum antibiotic formulation combining Piperacillin and Tazobactam, designed to effectively combat a wide range of bacterial infections, including those caused by β-lactamase producing organisms.

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Composition

• Piperacillin (as Sodium) – 4 g
• Tazobactam (as Sodium) – 0.5 g

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Pharmacological Action

Piperacillin works by inhibiting bacterial cell wall synthesis, leading to bacterial death. Tazobactam acts as a β-lactamase inhibitor, protecting Piperacillin from enzymatic degradation and enhancing its antibacterial spectrum.

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Indications

Indicated for the treatment of moderate to severe infections such as:

• Respiratory tract infections (including pneumonia)
• Urinary tract infections (UTIs)
• Intra-abdominal infections
• Skin and soft tissue infections
• Gynecological infections
• Septicemia
• Bone and joint infections

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Dosage & Administration

• For Intravenous (IV) or Intramuscular (IM) use only
• Dosage should be administered strictly under medical supervision, depending on infection severity and patient condition

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Key Advantages

• Broad-spectrum antibacterial coverage
• Effective against resistant and mixed infections
• Enhanced efficacy due to β-lactamase inhibition
• Preferred choice in hospital and critical care settings

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Precautions

• Use cautiously in patients with penicillin allergy
• Dose adjustment required in renal impairment
• Monitor for hypersensitivity reactions
• To be used only under qualified healthcare supervision

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Storage

• Store below 25°C in a dry place
• Protect from light

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Packaging

• Sterile powder vial for reconstitution