Terlipressin Injection – Terlin 1 mg/10 ml (For I.V. Use)
Terlipressin Injection – Terlin 1 mg/10 ml (For I.V. Use)
Description
Terlin Injection contains Terlipressin, a synthetic vasopressin analogue primarily used in emergency and critical care settings. It is widely indicated for the management of bleeding esophageal varices and hepatorenal syndrome, where rapid vasoconstriction is required.
Composition
- Terlipressin Acetate equivalent to Terlipressin – 1 mg/10 ml
Mechanism of Action
Terlipressin acts on vascular smooth muscle via vasopressin receptors, causing vasoconstriction, particularly in the splanchnic circulation. This reduces portal venous pressure, helping control variceal bleeding and improving renal perfusion in hepatorenal syndrome.
Indications
- Acute bleeding esophageal varices
- Hepatorenal syndrome (HRS)
- Portal hypertension-related complications
Dosage & Administration
- For Intravenous (I.V.) use only
- Administered by slow IV injection or infusion
- Dosage depends on indication and patient condition; must be given under strict medical supervision
Key Benefits
- Rapid control of variceal bleeding
- Improves renal function in HRS
- Long-acting vasopressin analogue
- Essential drug in emergency and ICU settings
Precautions
- Monitor blood pressure and cardiovascular status
- Use cautiously in patients with ischemic heart disease
- May cause abdominal cramps, hypertension, or bradycardia
- Strictly for hospital use
Storage
- Store in a cool, dry place below 25°C
- Protect from light
Packaging
- Ready-to-use liquid injection (10 ml vial/ampoule)
